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Day 2 // Breakout 4:

New developments in

Lorenzo Moroni (Chair of the session)

Lorenzo Moroni (Chair of the session) (Chairman)

Maastricht University, NL

Professor

Curriculum vitae

Dr. Lorenzo Moroni studied Biomedical Engineering at Polytechnic University of Milan, Italy, and Nanoscale Sciences at Chalmers Technical University, Sweden. He received his Ph.D. cum laude in 2006 at University of Twente on 3D scaffolds for osteochondral regeneration, for which he was awarded the European doctorate award in Biomaterials and Tissue Engineering from the European Society of Biomaterials (ESB). In 2007, he worked at Johns Hopkins University as a post-doctoral fellow in the Elisseeff lab, focusing on hydrogels and stem cells. In 2008, he was appointed the R&D director of the Musculoskeletal Tissue Bank of Rizzoli Orthopedic Institute, where he investigated the use of stem cells from alternative sources for cell banking, and the development of novel bioactive scaffolds for skeletal regeneration. From 2009 till 2014, he joined again University of Twente, where he got tenured in the Tissue Regeneration department. Since 2014 he works at Maastricht University and in 2016 he became professor in biofabrication for regenerative medicine at the MERLN Institute for Technology-Inspired Regenerative Medicine. His research group interests aim at developing biofabrication technologies to generate libraries of 3D scaffolds able to control cell fate. In 2014, he received the prestigious Jean Leray award for outstanding young principal investigators from the ESB and the ERC starting grant.

Horst Fischer

11:30 - Advances in Biofabrication: Submerged 3D Bioprinting of Cell-Laden Hydrogel Blends

Horst Fischer

Uniklinikum Aachen, DE

Curriculum vitae

Prof. Horst Fischer is head of the department Dental Materials and Biomaterials Research, RWTH Aachen University Hospital since 2009. He received his diploma in mechanical engineering in 1992 and his PhD in the field of biomaterials under the supervision of Prof. Horst R. Maier at RWTH Aachen University in 1995. Afterwards he worked with the American company Procter & Gamble in a research and development department. Back to the University, he received his habilitation in Biomedical Materials at RWTH Aachen University in 2002. Prof. Fischer is internationally recognized in the field of synthesis and characterization of novel biomaterials and its processing by tailored additive maufacturing techniques as for example cell‐laden hydrogel‐based 3D‐bioprinting. He is member of the working group 'Additive Manufacturing and 3D printing' of the National Academy of Science, Leopoldina.

Abstract

Recent years have revealed a remarkably increase in research activities in the field of biofabrication worldwide. The motivation for research and development on this topic is to treat in the future tissue defects by personalized three-dimensional tissue substitutes made of the patients' own cells and manufactured by 3D printing techniques. Hydrogels are a suitable class of materials to print cells due their cell-friendly and cell-supporting properties. However, a major challenge is the 3D build-up of hydrogel components with defined shape avoiding the hydrogels' deformation before the gelling process is completed. Here, a novel approach called 'Submerged 3D Bioprinting' technique is presented. It is shown that this printing technique in combination with novel hydrogel blends exhibits an encouraging perspective for the field of biofabrication.

11:50 - Pitches

Marco Vitr

IT4process GmbH, DE

Simon Dusauchoit

Typework, BE

Tim Kaufmann

enmodes GmbH, DE

Gabi Janssen

12:05 - Metal 3D printing in the implant industry: challenges and opportunities

Gabi Janssen

3DSYSTEMS, BE

Project Engineer, Healthcare

Curriculum vitae

To work as Project Engineer Healthcare for 3D Systems allows me to follow my dream combining both technical & medical fields to create innovative solutions.
Born in a medical family, I started my career with an internship in the technical department of the hospital UMC Utrecht, and I worked together with surgeons in research projects, which gave me a glance into the medical field. My (professional) experience -Account Manager in the high-tech sector of Eindhoven; 3D printing software development at Materialise; and now Project Engineer in direct metal printing at 3D Systems- gives me a broad overview of state-of-the-art technology in 3D printing.
Using example cases of 3D Systems I will share my passion and hope to inspire you to join the field where technology meets healthcare.

Abstract

This presentation will introduce you to the world of medical 3D (metal) printing. 3D printing makes it possible to manufacture designs using organic shapes, textures and scaffolds.

Using CT/MRI as input data allows personalized 3D applications. Complex procedures can be prepared with this 3D data. Visual models are shared with patients for better comprehension of complex problems. Previously unsolved medical cases can now find a solution utilizing these 3D printing technologies.

Biocompatible metal materials like Ti and CoCr have already introduced new implants to the market, in mass production and economically profitable. Short lead times for production also make the technology an attractive solution for patient-specific implants and prototyping.

Using the in house developed machines we print completely functional parts, of which I will show examples during the presentation.

I would like to share my lessons learned in 3D manufacturing to demonstrate some of the challenges in 3D printing. I believe these can also be seen as opportunities rather than limitations. It requires a new way of thinking but can lead the way for inventions of profitable new products.

I hope this presentation can inspire you to think differently, use your imagination and create the previously impossible solution.

12:25 - Pitches

Sebastian Schusser

FH Aachen - Campus Jülich, DE

Job Beckers

PlasmaPendix, an Eindhoven University of Technology spin-off, NL

Frédéric Lambrechts

Osimis, BE

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